Keynote lecturers
Final Programme
Wednesday, 30 June
10.00-14.00 | Registration |
14.00-14.30 | Welcome and commemoration of Arturo Falaschi |
DNA replication and replication dynamics | |
14.30-14.50 | Laura Marchetti: Homeotic proteins participate in the function of human-DNA replication origins. |
14.50-15.40 | Keynote Lecture John Diffley: Mechanism and Regulation of DNA Replication during the Cell Cycle and in Response to DNA Damage |
15.40-16.00 | Silvia Onesti: Structural basis of the MCM helicase activity |
16.00-16.30 | Alessandro Vindigni: Understanding the multiple roles of RecQ helicases in DNA replication |
16.30–17.00 | Coffee break |
17.00-17.30 | Luca Pellegrini: Structural biology of proteins important for DNA replication and repair |
17.30-18.00 | Vincenzo Costanzo: The role of Rad51 in DNA replication |
18.00-18.20 | Francesca Carlomagno: Protein NCOA4 is a novel inhibitor of DNA replication in mammals and Xenopus laevis |
18.20-18.40 | Federica Lo Sardo: Genetic and epigenetic heritability: PcG system and replication |
18.40-19.00 | Chiara Lanzuolo: Timing of PcG mediated epigenetic inheritance through S phase in Drosophila melanogaster |
19.30 | Dinner buffet |
Thursday, 1 July
DNA repair and recombination | |
9.00–9.50 | Keynote Lecture Alan Lehmann: Regulation of translesion synthesis in human cells |
9.50-10.20 | Miria Stefanini: NER-defective hereditary disorders |
10.20-10.40 | Donata Orioli: Insights into genotype-phenotype relationships in the repair/transcription syndrome Trichothiodystrophy |
10.40-11.00 | Ennio Prosperi: Investigating the role of p300 and CBP in nucleotide excision repair: interaction with NER factors |
11.00–11.20 | Coffee break |
11.20-11.40 | Marco Muzi-Falconi: Converging mechanisms for the full activation of the DNA damage checkpoint |
11.40-12.00 | Magda Granata: Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle regulated by CDK1 activity |
12.00-12.20 | Achille Pelliccioli: Mechanisms and factors involved in turning off the DNA damage checkpoint |
12.20-12.40 | Pietro Pichierri: Functional relevance of ATR phosphorylation of the Werner syndrome protein in response to replication stress |
12.40-13.00 | Silvia Baldari: Mechanisms of genome stability at common fragile sites - Regulation of checkpoint activation |
13.00–14.30 | Lunch |
14.30–16.00 | Poster session |
16.00-16.20 | Evandro Panico: Yeast Mph1 is an important factor for the fine tuning of recombinational DNA repair under replicative stress |
16.20-16.40 | Emanuele Crespan: DNA polymerase Lambda specifically bridges and extends DNA ends containing microhomology regions and is supported by interaction with the 9-1-1 complex |
16.40-17.00 | Maria Ciaramella: A novel pathway for Holliday junction resolution revealed by archaeal reverse gyrase |
17.00–17.20 | Coffee break |
17.20-17.40 | Adriana La Volpe: Roles of the BRCA1 and FANCD2 orthologs in meiosis and genome stability in Caenorhabditis elegans |
17.40-18.00 | Aurora Storlazzi: Sordaria macrospora: a model system to study pairing of meiotic chromosomes |
18.00-18.30 | Margherita Bignami: Biochemical and functional characterization of MUTYH mutations associated with Familial Adenomatous Polyposis |
18.30-18.50 | Maria Teresa Russo: Oxidative damage, aging and mitochondrial DNA stability: is there a relationship |
20.30 | Conference dinner |
Friday, 2 July
Genome instability | |
9.00–9.50 | Keynote Lecture Andreas Aguilera: Recombination-mediated genome instability: from transcription to nucleotide excision repair |
09.50-10.10 | Alessandra Montecucco: Pre-mRNA processing factors meet the DNA damage responses |
10.10-10.30 | Corrado Santocanale: Addressing the role of human Cdc7 kinase in the DNA replication checkpoint |
10.30-10.50 | Ivana Murfuni: Investigation of the MUS81-dependent pathway in the absence of the replication checkpoint and analysis of its regulation |
10.50–11.20 | Coffee break |
11.20-11.40 | Francesco Merolla: Cell cycle dependent regulation of CCDC6 gene product: functional interaction with mitotic kinases and the catalytic subunit of Protein Phosphatase 4 |
11.40-12.00 | Thomas Carzaniga: Polynucleotide phosphorylase has 3’ to 5’ exonuclease and template-independent DNA polymerase activities on single-stranded DNA in bacteria |
12.00-12.30 | Maurizio Gatti: Drosophila telomeres: structure, evolution and role in cell cycle control |
12.30–12.40 | Closing Remarks |
In preparing your poster/oral presentation, please take note of the following points: